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Propranolol

FDA Approved
Membrane IntercalationOral

Description

Propranolol is a non-selective beta-blocker used to treat hypertension, anxiety, and other conditions. Its lipophilic properties enable CNS penetration and membrane interactions.

Chemical Properties

Molecular FormulaC16H21NO2
Molecular Weight259.3 g/mol
Oral Bioavailability25%
CAS Number525-66-6
DrugBank IDDB00571
PubChem CID4946
SMILES
CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O

Membrane Intercalation Mechanism

Beta-blockers like propranolol are amphiphilic molecules that partition into lipid membranes, affecting membrane properties and accessing membrane-bound adrenergic receptors.