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Escitalopram
FDA Approved
Membrane IntercalationOral
Description
Escitalopram is the S-enantiomer of citalopram, an SSRI antidepressant. Its membrane-active properties allow effective penetration into CNS tissue and transporter interaction.
Chemical Properties
Molecular FormulaC20H21FN2O
Molecular Weight324.4 g/mol
Oral Bioavailability80%
CAS Number128196-01-0
DrugBank IDDB01175
PubChem CID146570
SMILES
CN1C2=C(C=CC(=C2)C#N)C(C3=CC=CC=C31)(C4=CC(=C(C=C4)F)F)O
Membrane Intercalation Mechanism
Escitalopram's aromatic structure and fluorine atoms enable membrane integration and selective binding to serotonin transporters in synaptic membranes.