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Metoprolol
FDA Approved
Membrane IntercalationOral
Description
Metoprolol is a selective beta-1 adrenergic receptor blocker used to treat hypertension and angina. Its membrane interaction is essential for receptor binding.
Chemical Properties
Molecular FormulaC15H25NO3
Molecular Weight267.4 g/mol
Oral Bioavailability50%
CAS Number37350-58-6
DrugBank IDDB00264
PubChem CID4171
SMILES
COC1=CC=C(C=C1)CCOC(CNC(C)C)O
Membrane Intercalation Mechanism
Beta-blockers like metoprolol are amphiphilic molecules that partition into cardiac cell membranes to access beta-adrenergic receptors embedded within the membrane.